Targeting a Genetic Accident to Treat Disease

 David Liu

David Liu is a professor in the Department of Chemistry and Chemical Biology at Harvard University. Liu’s lab has introduced breakthrough technologies to the field of genome editing, including base editing and prime editing, with the aim of treating genetic diseases. In their latest work, his research team took a “no stone unturned” approach to determine a one-time base editing strategy to treat the motor neuron disease, spinal muscular atrophy (SMA). In this episode, Deanna MacNeil from The Scientist’s Creative Services Team spoke with Liu to learn more about his philosophy of science, which involves an appreciation of fundamental principles in chemistry and evolution.

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Science Philosophy in a Flash is a series of mini podcasts produced by The Scientist’s Creative Services Team. With a focus on the people behind the science, this podcast highlights researchers’ unique outlook on what motivates their pursuit of science and what it means to be a scientist. 

David Liu

David Liu, PhD
Richard Merkin Professor
Director, Merkin Institute of Transformative Technologies in Healthcare
Director, Chemical Biology and Therapeutic Sciences Program
Thomas Dudley Cabot Professor, Natural Sciences
Professor, Chemistry and Chemical Biology
Harvard University
Core Institute Member and Faculty Vice-Chair, Broad Institute
Investigator, Howard Hughes Medical Institute

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